what's the matter... arggh

aw!! what is the problem with my template??? in the beginning everything was fine and aligned how come as I progress through my revisions on the layout it turned out to be a disaster in the end... just like this tags on the side. they won't load although i have resized it to smaller size and sometimes just moves over to the left so it leaves the texts out of place..... please help me.. how to I edit this layout.... I'm getting tired of loading and editing.. and adjusting.. please please please